Gemma 4 26B A4B has 26B parameters (MoE: 4B active per forward pass, but all 26B must fit in memory). At FP16 that's 52 GB of raw weights. Quantization shrinks that, but you also need budget for the KV cache (definition), framework overhead, and safety headroom. The rule of thumb: real usable budget on a card is roughly its nameplate VRAM minus 25%. That's how the table below was computed.
Smallest GPU that fits Gemma 4 26B A4B at any quant: H100 80GB at FP16/BF16.
Lossless inference needs 52 GB. Pick from 13 cards.
Q5_K_M fits comfortably (18 GB weights).
Open the calculator pre-tuned for Gemma 4 26B A4B: ↗ /calc?model=gemma-4-26b
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