Short answer: yes, on a M3 Ultra 512 (512GB) at FP16/BF16. Long answer below.
Command R+ has 104B parameters. At FP16 that's 208 GB of raw weights. Quantization shrinks that, but you also need budget for the KV cache (definition), framework overhead, and safety headroom. The rule of thumb: real usable budget on a card is roughly its nameplate VRAM minus 25%. That's how the table below was computed.
Smallest GPU that fits Command R+ at any quant: M3 Ultra 512 at FP16/BF16.
Lossless inference needs 208 GB. Pick from 1 cards.
None of the showcase quants fit on a 24GB card. Step up.
Open the calculator pre-tuned for Command R+: ↗ /calc?model=command-r-plus
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